Our lab is dedicated to advancing understanding in musculoskeletal mechanobiology by combining cutting edge mechanics, imaging, and biological techniques
Welcome to the Lewis Lab
We focus on understanding the interplay of mechanical cues and biological changes in musculoskeletal tissues. Specifically, we interrogate how the acute sensing mechanisms in musculoskeletal cells relate to tissue level changes in healthy and disease states. Our investigations in bone are focused on understanding how bone cells interpret mechanical loading in real time using intravital imaging techniques. Additionally, we are interested in understanding how bone interacts with other neighboring tissues in the onset and progression of diseases like osteoarthritis and osteoporosis.